The world is witnessing momentous shifts in geopolitics, and in fact, in every facet of human life. The US-China zero-sum game for dominance may well define pathways nations take to bring prosperity to their people in the next decade. This paper attempts to track current issues of this ‘race’ especially after a change of presidency in the US. In particular, issues in the Indo-Pacific in terms of fast-changing policies of both powers are explored from the Indian perspective.